Now a major motion picture from Universal Studios, starring Bradley Cooper, Robert DeNiro, and Abbie Cornish. §Eddie Spinola could use a shot in the arm. Burned out at thirty-five, months behind on his book, low on cash, and something of a loser, one day he randomly runs into Vernon, his ex-wifes brother, and his ex-dealer. Now employed by a shadowy pharmaceutical company, Vernon has something that might help: a new designer drug that stimulates brain function. One pill and Eddie is hooked. His book is finished within days; he learns and synthesizes information at a frightening rate; and he can go a long time without sleep or food. Naturally, he begins to play the stocks. But when Vernon turns up dead, Eddie makes off with the only stash of the drug in existence. Then come the side effects: black-outs, blinding headaches, and violent outbursts he cant seem to remember.