In the late 26th century, overpopulation on Earth is reaching the breaking point, and humanity must find new frontiers. The terraforming of Mars has taken centuries but is now complete. The colonization of Mars by humanity is an epoch-making event, but an unintended side effect of the terraforming process unleashes a horror no one could ever have imagined... A new mission to Mars, Annex 1, is under way. Their mission: crucial research into the A. E. Virus currently plaguing mankind. The mutant Terraformars, giant humanoid cockroaches, may hold the key to a cure. Unfortunately for the crew of the Annex 1, the Terraformars have somehow gotten on board the ship and have only one goal - total extermination! Led by Akari Hizamaru, the crew will need to rely on their superhuman powers to survive... if those powers don't kill them first!